Objective To investigate DATS inducing MGC - 803 cell apoptosis and its possible mechanism.

目的　探讨二烯丙基三硫(diallydisulfide,DATS)诱导人胃癌MGC - 803细胞凋亡及作用机制.

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Objective To investigate whether DATS induces apoptosis in MGC - 803 cells.

目的探讨二烯丙基三硫(diallyltrisulfede,DATS)诱导人胃癌MGC -803 细胞凋亡的作用.

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CONCLUSION: DATS induces apoptosis in MGC 803 cells which may be through the activation of caspase - 3 pathway.

结论: DATS诱导人胃癌MGC803细胞凋亡可能与活化Caspase -3 有关.

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Conclusion Bcl - 2 gene family may participate in the DATS induced apoptosis of MGC - 803 cells.

结论Bcl -2 基因家族可能参与了DATS诱导的MGC -803 细胞凋亡.

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Diallyl trisulfide ( DATS ) is a major anticancer ingredient from the bulb of garlic of liliaceous plants.

大蒜素(allitrid)为百合科植物大蒜(alliumsativumL. ) 鳞茎中所含的一种抗癌活性成分,化学名称为二烯丙基三硫化物 ( diallyltrisulfide,DATS).

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Aim To investigate whether DATS induce MGC 803 cell apoptosis and the relationship betweenapoptosis and Ca ~ ( 2 + ) disruption.

目的探讨二烯丙基三硫(DATS ) 对人胃癌MGC803细胞的促凋亡作用及钙稳态失衡与该作用的相关性.

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However , DATS alone had on effect on the production and mRNA expression of TNF - α, IL - 1? ? ( P ＞0.05 ).

单独DATS对TNF - α及IL-1β的生成及其mRNA表达 无明显影响 ( P>0.05 ).

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Moreover, pro - caspase 3 was hydrolyzed and activated in DATS - treated MGC 803 cells.

Westernblot显示酶原形式的Caspase-3被水解活化.

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It also can raise the dats accuracy to determine the earth air density.

也可提高用于反测地球大气密度的资料的精度.

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