The coupling reaction between the difficult sequence Fmoc - Arg ( Pbf ) - OH and H - Pro - Trt resin was investigated.

着重研究了 Fmoc -Arg ( Pbf ) -OH与H -Pro-Trt 树脂的缩合反应.

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The synthesis of cyclo ( - Ab 7 - Aib - Phe - D - Pro - ) which uses solid phase peptide synthesis with N - Fmoc protection is faild.

本论文尝试用固相法氨基酸N端Fmoc保护策略合成cyclo ( -Ab7-Aib-Phe-D-Pro- ).但是最终产物经ESI-MS分析不是目标产物,故改用液相法合成目标化合物.

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Fmoc, Boc and Pbf were used respectively to protect α - amido, side amido and side guanidine group.

对于α-氨基仍采用Fmoc保护策略, 侧链氨基用二碳酸二叔丁酯引入叔丁氧羰基来保护,侧链胍基用酸敏感保护基2,2, 4,6,7-五甲基二氢苯并呋喃-5-磺酰基来保护.

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The esterification process of Fmoc - Asn ( Trt ) - OH and Wang resin was studied by solid phase synthesis.

研究了 Fmoc -Asn ( Trt ) -OH与Wang树脂的酯化反应工艺.

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And the L - Lys containsside chain ammonia , the protected product is Fmoc - L - Lys ( Boc ).

含侧链氨基的L - 赖氨酸, 所合成的正交保护的L - 赖氨酸是 Fmoc -L-Lys ( Boc ).

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