Objective To explore the specific pathogenic role of glycation products in normal kidney.

目的为探讨糖基化产物对正常肾脏的特异性损害作用.

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Methed: The animals concentration of blood glucose, lipids and advanced glycation end products plasma were investigated.

方法: 观察该方对链脲佐菌素诱导的糖尿病大鼠血糖 、 血脂、蛋白质糖化终末产物的影响.

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RESULTS Inactivation of esterase was induced by glycation, carbamylation and steroid in a concentration.

结果糖化 、 氨甲酰化和类固醇诱导酯酶失活的作用呈浓度依赖性,类固醇失活效应最快.

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Conclusion: CSMH may inhibit non - enzymatic glycation and vascular dysfunction in kidney of STZ - induced diabetic rat.

结论: 酸味中药复方对糖尿病大鼠肾的 非 酶糖化反应和血管病变有一定的抑制作用.

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