Overexpression of ILK in HKC tansfered with pCMV - wtILK could induce FN expression.

转染pCMV-wtILK质粒的HKC细胞,其FN的表达呈增加趋势.

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ConclusionThere is an additive effect but no synergism between IGF - I and TGF - ? ? 1 on EMT.

IGF-I 和TGF - β1对诱导HKC转化无协同作用.

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Methods: Using cell culture and Western blot, the TGF - ? ? 1 - induced expression of FN and ILK was tested.

方法培养人肾小管上皮细胞(HKC),用蛋白印迹方法检测TGF - β1诱导HKC合成 FN和表达ILK的作用.

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