ConclusionNE - induced rat cardiac remodeling decreased the GSK - 3? ? protein and increased in DVL - 1 protein in cardiofibroblasts.

结论NE致 大鼠心肌重塑过程中GSK -3 β蛋白表达显著降低,DVL-1蛋白表达显著升高,可能与心肌纤维化有关.

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ObjectiveTo observe the expression of GSK - 3? ? and DVL - 1 protein cardiofibroblasts in cardiac remodeling in rats.

目的观察大鼠心肌重塑过程中心肌成纤维细胞DVL-1蛋白及糖原合酶激酶 -3 β(GSK -3 β)蛋白表达变化.

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Communication and coordination with GSK quality leadership team, quality audit team and AP quality team.

与相应GSK质量管理团队 、 质量审计团队,亚太区质量团队沟通协调.

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MAPK inhibitor ( PD 98059 ) inhibited the phosphorylation of GSK - 3 P and almost completely blocked oxLDL - induced tubular EMT.

MAPK抑制剂 PD98059 可抑制GSK -3 β的磷酸活化,并几乎完全阻断oxLDL诱导的肾小管上皮细胞转分化,但对LDL诱导 的小管上皮细胞转分化只有部分阻断作用.

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Notably, treating mice with GSK - 3 inhibitor showed a decrease in LPS - induced renal cell apoptosis in vivo.

除了抗发炎作用, GSK -3 抑制剂可以降低体内LPS诱发小鼠肾脏组织中的细胞凋亡现象.

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Mr Witty, however , has already announced big changes at GSK.

Witty先生也已经宣布要对葛兰素史克动大手术.

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The gesture remains largely symbolic for GSK, however.

但对葛兰素史克来说, 这一姿态基本上仍只有象征意义.

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The unusual arrangement will give London - based GSK 85 percent equity and New York's Pfizer the remainder.

这项非同寻常的协议规定,总部在伦敦的葛兰素史克占了其中85%的股份,而剩下的归纽约的辉瑞所有.

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GSK's vaccine development won't be part of the new company, according to Bloomberg News.

彭博新闻社消息称,葛兰素史克的疫苗开发部将不会差与新公司的组建.

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Among the institutional grants was a GlaxoSmithKline Institute for Digestie Health Research award.

公共机构奖励的是葛兰素史克公司(GSK)的消化健康研究奖.

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