Objective : To approach the relationship between oncogene C - fos , K - ras and intrahep atic cholangiocarcinoma ( ICC ) and the significance.

目的: 探讨癌基因产物C -fos 、 K -ras 蛋白与肝内胆管癌发生的关系及其生物学意义.

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Objective : To confirm the cleavage activity of ribozyme Rz 199 to oncogene K ras messenger RNA.

目的: 确定人工设计的核酶Rz199对原癌基因K-rasmRNA的体外切割活性,为K-ras特异性核酶的体内应用提供依据.

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