In contrast, APL cells of two cases showed synergistic differentiation after treatment with ATAR and bufalin.

为了进一步研究蟾蜍灵对ATRA诱导分化的增强效应, 我们研究蟾蜍灵与维甲酸联合对APL原 代培养细胞的诱导分化作用.

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After treated with bufalin , the expressions of protein p 16, p 21 and pRb were up - regulated.

4蟾蜍灵作用于胃癌MGC803细胞,观察到p16 、 p21、 pRb 蛋白的表达明显上调.

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