Conclusion Over expression of PAI 1 gene leads to mesangial ECM accumulation.

结论　首次建立了系膜细胞PAI1 的过度表达体系,证实细胞过度表达PAI1可以直接导致ECM的积聚.

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Result Nicardipine can induce rat mesangial cell apoptosis in vivo.

结论尼卡地平在体内有诱导大鼠系膜细胞凋亡的作用.

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Mesangial cell nuclei showed irregular shape and mitochondria swelled, stroma was normal.

系膜细胞核不规则,胞质内线粒体肿胀.系膜基质正常.

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PGF _ 2α, U 46619 LTC _ 4 , LTD _ 4 also increased mesangial cell Diacylglycerol ( DAG ) mass levels.

PGF2α 、 U46619、LTC4、LTD4促进系膜细胞合成二脂酰甘油 ( diacylglycerol,DAG ).

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Objective To study the effect of nicardipine on rat mesangial cell apoptosis in vivo.

目的探讨尼卡地平体内对大鼠系膜细胞凋亡的诱导作用.

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The normal mesangium contains about 2 to 4 mesangial cells, a macrophage - like function.

正常系膜含2～4个具有巨噬细胞的功能的系膜细胞.

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Objective : To investigate the mechanism inducing apptosis of human glomerular mesangial cells ( Mcs ) by anti Fas antibody.

目的: 研究抗Fas抗体 对人肾小球系膜细胞的致凋亡作用,探讨Fas? FasL 在肾脏损伤中的作用.

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Objective Diagnosis and treatment experience of primary nephrotic syndrome mesangial proliferative glomerulonephritis are discussedthe article.

总结原发性肾病综合征系膜增生性肾小球肾炎的诊治经验.

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