Objective To establish a multidrug resistance cell line from human lung adenocarcinoma.

目的建立人肺腺癌多药耐药细胞系.

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Multidrug resistance is most common reason related to the failure of chemotherapy in leukemia.

多药耐药是白血病化疗失败的主要原因,也是白血病彻底治愈的最大障碍.

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Objective : To summarize resistance reversal agent and new reversal strategies on multidrug resistance of cancer cell.

目的: 综述肿瘤多药耐药逆转剂及逆转策略.

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Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure.

临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药(MDR).

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Hence, it is very important to further study the non - classical mechanism of multidrug resistance.

因此, 进一步了解 非 经典的耐药途径对于完善多药耐药机制有重要意义.

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Drug delivery system ( DDS ) is a novel approach to overcome multidrug resistance ( MDR ) in tumors nowadays.

药物递送系统是克服肿瘤多药耐药性 ( MDR ) 的一种新策略.

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The multidrug resistance , including intrinsic multidrug resistanceacquired multidrug resistance, is a major problem in tumor chemotherapy.

但在肿瘤化疗中,肿瘤的多药耐药(Multidrugresistance, MDR) 是肿瘤临床治疗的一大难题.

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