Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.

泛素 - 蛋白酶体途径是真核细胞内一种高效蛋白降解途径.

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So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer.

泛素介导的蛋白质降解途径的异常与许多疾病特别是肿瘤的发生密切相关.

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Conclusion: GFPu - 1 clonal cells may be a sensitive indicator for the function of the ubiquitin - proteasome system.

结论: GFPu -1 克隆细胞是一种反映UPS功能的敏感指标.

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