C - ski is transcriptional co - repressors that inhibit transforming growth factor - beta ( TGF - beta ) signaling through interaction with Smad 3, Smad 2 protein.

同时,近些年研究表明TGF -beta 信号系统是导致瘢痕形成的重要原因,而Smad3和Smad2做为TGF -beta 途径重要的信号因子,在瘢痕形成中具有重要作用, 因此,抑制Smad3和Smad2成为了减轻瘢痕形成的新途径.

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Messenger RNA levels of transforming growth factor - ? ? 1 ( TGF - ? ? 1 ) and connective tissue growth factor ( CTGF ) were determined using RT - PCR.

逆转录PCR检测转化生长因子 - β1 ( TGF - β1 ) 和结缔组织生长因子 ( CTGF ) mRNA水平.

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