Objective To establish a method for determination of amiodarone hydrochloride dispersible tablets with HPLC.

目的建立盐酸胺碘酮分散片中盐酸胺碘酮含量测定方法.

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HPLC method was established for determination of the related substances amiodarone hydrochloride and its dispersible tablets.

建立了HPLC法测定盐酸胺碘酮及其分散片的有关物质.

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Amiodarone hydrochloride is a hydrophobic drug, so its internal absorption is affected by preparation factors greatly.

盐酸胺碘酮难溶于水, 因此其体内吸收受剂型因素影响较大.

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